2019

THE HUMAN FORESKIN

The MISSING PIECE

THE HUMAN
FORESKIN

THE MISSING PIECE

The Foreskin

What it is. What it does.
Why it matters.

The foreskin is not an optional extra for a man’s body, nor is it a birth defect or accident. It is an integral, functioning, important component of a man’s penis. An eye does not function properly without an eyelid – and nor does a penis without its foreskin.

Protection

The foreskin fully covers the glans (head) of the flaccid penis, thereby protecting it from damage and harsh rubbing against abrasive agents (underwear, etc.) and maintaining its sensitivity.

Sexual Activity

The foreskin facilitates direct stimulation of the glans during sexual activity by its interactive contact with the sensitive glans.

Lubrication

The foreskin, with its unique mucous membrane, permanently lubricates the glans, thus improving sensitivity and aiding smoother intercourse.

Sexual Sensation

The foreskin provides direct sexual pleasure in its own right, as it contains the highest concentration of nerve endings on the penis.

Immune System

The foreskin helps clean and protect the glans via the secretion of anti-bacterial agents, including Langerhans cells which can destroy HIV.

Skin Gliding

The foreskin facilitates the necessary gliding and expansion of skin on the penile shaft and glans, providing for natural sensations and retaining lubricating fluids during intercourse.

What Foregen is trying to give back to you

Anatomy of the Foreskin: 
Four Distinct Structures

Visuals

The Inner Foreskin

The inner foreskin is smooth mucosal tissue, much like the inside of your mouth. The inner foreskin is packed with nerve endings and is designed to stimulate the glans penis while feeling slight variations in pressure and stretching, subtle variations in temperature, and fine gradations in texture.

Visuals

The Outer Foreskin

The outer foreskin is an essential continuation of the shaft skin. It keeps the glans penis protected and sensitive so it is ever-ready to respond to stimuli. It facilitates intercourse by mitigating friction and acting mechanically as a roller-gliding bearing which retains sexual fluids and helps prevents painful intercourse.

Visuals

The Ridged Band

The ridged band (sometimes called the “frenar band”) is a primary erogenous zone on the male body. This unique, highly specialized, and exquisitely sensitive structure is equipped with soft ridges designed by nature to stimulate the female’s inner labia and G-spot during intercourse. Ribbed condoms attempt to mimic this unique structure.

Visuals

The Frenulum

The frenulum, another primary erogenous zone on the male body, is a highly sensitive V-shaped tethering structure on the underside of the head of the penis. The frenulum connects the ridged band to the glans penis. It contains vascular structures and extreme innervation. The highly sensitive frenulum is often referenced in sexual health culture, but is almost always removed in circumcision.

Understanding the Foreskin's Shape
The butterfly-like shape of the foreskin model shown here may be confusing at first glance. Since the foreskin is a specialized bi-layer tissue, its unfolded shape can be hard to recognize. To better understand this unique tissue, shown above is a schematic representation of the human foreskin after circumcision and the sequential steps performed to identify the shape of the foreskin's bi-layer nature.

Foregen's goal is full regeneration of the foreskin.

The foreskin: regaining sensitivity, pleasure, and function.

Regenerating the foreskin has two main aims:

•To reverse the harm done by circumcision.

•To bring back the sexual sensitivity, normal function, bodily completeness and psychological well-being of the healthy adult male that wishes to have his foreskin back, allowing the once-circumcised man to function normally in sexual intercourse (and in daily life) as nature intended.

No human foreskin has ever been regenerated by medical science. At best, foreskin restoration therapies can stretch the normal shaft skin left after circumcision to mimic the effect of a foreskin (known as “restoring”) but this never replaces the unique properties and functions of the real foreskin with which every baby boy is born.

Foregen is dedicated to changing that. Foregen’s mission is to harness regenerative biomedical knowledge and tissue engineering techniques to genital reconstruction for circumcised men, and to produce a therapy which will bring back the original tissue, function, and structure ablated by circumcision. Only when true foreskin regeneration is possible can the harms done by circumcision be reversed – and the benefits of being intact regained.

The benefits of an inner foreskin.

Regenerating the foreskin will increase the sensitivity of the glans, given that it will be covered and protected by the inner foreskin - a mucous membrane that prevents the glans from external abrasion.

Our procedure would lead to dekeratinization, a process whereby the layers of cells that developed (or keratinized) to protect the sensitive surface of the glans from outside abrasion is reversed. This causes the tissues normally covered by the foreskin, namely the glans penis, to become more sensitive to touch, providing for superior lubrication and a natural appearance.

A bi-layer tissue and a natural appearance.

The foreskin’s bi-layer tissue - inner and outer foreskin - would also be restored, giving men a greater surface area of skin on their penis (with a large number of nerve endings), part or all of the frenulum, the mucosal lining of the inner foreskin, and thus more pleasure. This would also serve to help men retain sensitivity as they age, as well as help older men regain sensitivity.

Foregen’s planned procedure would help to restore the natural look of the penis, keep the glans in its proper environment, and remove scarring that accompanies circumcision. Foregen’s procedure may also have a significant application for the many victims of botched circumcisions.

Sexual pleasure restored.

During sex the foreskin would provide a man with the feeling of all the nerve endings, as well as a very sensitive glans that is only exposed to touch during sex. Secondly, the presence of a foreskin allows for the abundant skin present along the shaft to glide onto the glans, providing its own stimulation and retention of natural lubricating fluids.

The stretching and relaxing of the foreskin and frenulum as the skin of the penis is pushed forward and back during intercourse is also another source of pleasure that is provided by the foreskin. The foreskin and its substructures are a major component of the pleasure and ejaculatory response in intact males.

Finally, when a man is not sexually active, the foreskin will cover the glans again, protecting it and preserving its sensitive state.