At Foregen, our mission to develop a regenerative medicine solution for foreskin restoration is driven by more than just groundbreaking science—it's fueled by a profound, unmet human need.
Our recent white paper outlines the ethical and scientific framework for our work, but the most compelling evidence lies in the personal stories of men who feel a deep sense of loss.
A Sensory and Psychological Loss
The male foreskin is far more than a simple fold of skin; it is a complex, highly innervated tissue vital for sensation and sexual function. According to a 2007 study, circumcision "ablates the most sensitive parts of the penis." This anatomical and sensory loss leads to widespread regret and a deep sense of incompleteness.
We often hear from men who express this loss directly. Here are just a few of the testimonies shared with us:
“I’ve spent much of my adult life becoming increasingly aware of the physical and psychological impacts it has had on me... Foregen's work in regenerative medicine represents a powerful hope for restoring bodily integrity and improving quality of life for men like myself.”
“I want mine back. It makes me cry every time I think about it—having part of my body forcibly removed against my will as a child, and I can never get it back. It's sick.”
The Demand is Massive
These are not isolated feelings. To quantify this profound demand, we sponsored a survey in 2022 that delivered an astonishing finding:
An estimated 21% of circumcised males in the U.S.—approximately 18.3 million men—would potentially consider a surgical procedure to regrow their foreskin and fully reverse their circumcision.
This immense figure confirms that we are addressing a critical, overlooked crisis. This enduring desire for restoration, rooted in the suffering of those who have been harmed, directly fuels our dedication to creating a tangible path for men to reclaim their bodily integrity and function.
How You Can Help Us Meet This Need
Foregen is committed to making this world's first biologically restorative solution a reality. We are currently advancing our preclinical research to perfect the tissue engineering protocols that will serve as the foundation for human clinical trials.
Your continued support is essential to closing the gap between the profound need for restoration and the realization of our scientific solution.
Read the full story behind our mission in the White Paper
Thank you for being a vital part of this movement toward healing and wholeness.