Tyler Drozd commented on The Foregen Future Newsletter #20 May 4th, 2018 2018-05-04 19:25:14 -0400Hi Ronald,
We stated this in the last newsletter, that the current research is in for peer review with “[the] Journal of Tissue Engineering and Regenerative Medicine with additional tests on traction. After decellularization, the foreskins are probed to see if they react to the mechanical stresses the same way as if they were living foreskins on a human body alive. According to Dr. Purpura’s estimate, this should be finished in about two months with the editor looking over the work along with comments from the reviewers it is sent to, given that the journal accepts the finalized paper.”
Once that is finished we’ll be looking to go for profit by the end of the summer and continue with our research.
Tyler Drozd commented on The Foregen Future Newsletter #15 February 16th, 2018 2018-02-17 22:25:25 -0500Hi Ronald,
We finished up our last set of experiments and are currently in the process of getting them published.
The results of those experiments were complete decellularization of the human foreskin, in other words the removal of all living donor tissue, and standing up to all mechanical tests to make sure they would be viable under all the stresses a foreskin would normally be placed under.
As far as trials go we haven’t promised a start date on human clinical trials, only an estimate for 2019 when we’re looking to start to them.
Hopefully this helps,
Tyler Drozd commented on The Foregen Future Newsletter #7 October 1st, 2017 2017-10-12 13:09:30 -0400Hi Brianna,
If your husband is interested he can sign up to be considered for human clinical trials here:
This isn’t a guarantee he will be selected but it does put his name down as someone who would like to participate. It’s also no binding, so if he does get chosen in the future he can also decline to participate if he changes his mind.
Hopefully this helps answer your question! Let us know if there’s anything else we can help you with!
Tyler Drozd commented on Decellularization Experiments and Next Steps 2017-04-02 17:52:07 -0400Hi Zachary. We’ve mentioned a possible transition to a for-profit entity in the past and have tried to be upfront about it so it doesn’t come as a surprise. We’re also wary of course of who we accept investment from and want to make sure our goal of restoring genital integrity to every one who wants it isn’t compromised in the process. I just wanted to let you know we share your concerns as well. We do see this path ahead as the best since it will provide us with the funds we need to carry out our research into the future. Donations have taken us this far but we will need more money to complete future phases of our research and hire other scientists, for example. Without it our research would likely take longer than our supporters expect or want.
Tyler Drozd commented on Update from the Foregen Labs on our Human Tissue Experiments: August 2016 2016-08-08 18:49:03 -0400Hey Julian!
You’re right there isn’t a lot of activity here and I think I’ll try to comment as well more often. In the meantime you should check out Foregen’s facebook which is very active. Also, I’m a moderator on the subreddit for Foregen so you should check that out to! My username on reddit is Tyfett by the way.
Tyler Drozd donated 2018-03-05 11:26:40 -0500
In order for us to continue the research and make real progress in the field of regenerative medicine of the foreskin, we need to spend about 3 million on research. Of course, we want to achieve our goals sooner rather than later. So our goal is 5 years. That means we need to raise approximately $50,000/month for the next 5 years.
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Human Clinical Trial
Foregen's major objective is to fund a clinical trial of foreskin regeneration in the circumcised adult male.
Medical research has made true dermal regeneration possible to a greater extent than ever before (for more on the science side of things, see our page on The Science of Regeneration). However, foreskin regeneration has not yet been tried, despite our knowledge that foreskin fibroblasts respond extremely well to regenerative technologies which create new skin. Foregen believes that it is time such a trial was undertaken.
What kind of trial?
Foregen will conduct a trial to reattach regenerated foreskins to circumcised adult males to restore the vascularity, nerve endings, and function that are excised during circumcision.
How will we get there?
Foregen's road map towards our ultimate goal of male foreskin regeneration is as follows:
- We will raise funds
- We will use our scientific panel to find the facility and recruit the researchers who are most likely to perform research which will lead to a clinical trial
- We will complete any necessary laboratory and pilot research and publish these results in a peer-reviewed journal
- Finally, we will carry out a clinical trial
We are currently on step 3 of our journey
Step 3 consists of fully regenerating animal foreskins and then conducting the same experiments on human foreskin. These results will be published in a peer-reviewed journal.
Of course, this road map is a simplification. There are complexities and uncertainties in such a trial as there are in any clinical trial that pioneers something new. Foregen cannot guarantee the final outcome or predict unforeseen obstacles that may fall in our way. However, Foregen recognizes the need for such a trial. We know how much success dermal regeneration has had in other areas, so we have good reason to believe that it will succeed in ours. While the outcome is not, and cannot, be certain, it is clear that we must try.
Interested in Participating? Read below...
The trials will be controlled and have the proper governmental approval. The trials will not be conducted by Foregen personnel, but rather by medical professionals adhering to the highest ethical standards of practice and research.
Currently we are actively recruiting trial participants who are:
- Males over the age of 18
- Circumcised, but not otherwise suffering from other health problems
A clinical trial is estimated to take up to eight weeks, though not all of that period will be spent under medical supervision. If you satisfy the above requirements and are interested in volunteering for this trial, we would be happy to hear from you. All medical care will be provided free of charge and you will be able to withdraw from the trial at any stage.
Volunteering for this clinical trial makes you eligible to benefit first from the most advanced medical technologies available for foreskin regeneration. However, such participation, like all medical procedures, carries some risk. The medical professionals conducting the trial will discuss with you the full range of options, possibilities, and dangers in order to assess your suitability for a trial. They will also, of course, need to obtain your full informed consent to participate in the trial.
Any person who indicates an interest is not under any obligation if you lose interest, you will be removed from our list of potential participants upon request. (But we don’t think you’ll want to!)
Still Interested? Create an account and signup below!
* Please note, this does not enroll you in future clinical trials, it simply ensures you receive relavent information regarding those trials as it becomes available.